Unknown

Dataset Information

0

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos.


ABSTRACT: Motivation: During development, progenitor cells undergo multiple rounds of cellular divisions during which transcriptional programs must be faithfully propagated. Investigating the timing of transcriptional activation, which is a highly stochastic phenomenon, requires the analysis of large amounts of data. In order to perform automatic image analysis of transcriptional activation, we developed a software that segments and tracks both small and large objects, leading the user from raw data up to the results in their final form.

Results: MitoTrack is a user-friendly open-access integrated software that performs the specific dual task of reporting the precise timing of transcriptional activation while keeping lineage tree history for each nucleus of a living developing embryo. The software works automatically but provides the possibility to easily supervise, correct and validate each step.

Availability and implementation: MitoTrack is an open source Python software, embedded within a graphical user interface (download here).

Supplementary information: Supplementary data are available at Bioinformatics online.

SUBMITTER: Trullo A 

PROVIDER: S-EPMC7703790 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4212533 | biostudies-literature
| S-EPMC6267562 | biostudies-literature
| S-EPMC10936412 | biostudies-literature
| S-EPMC3215701 | biostudies-literature
| S-EPMC3853218 | biostudies-literature
| S-EPMC7214047 | biostudies-literature
| S-EPMC5854467 | biostudies-literature
2020-03-03 | PXD009815 | Pride
2013-06-13 | GSE40748 | GEO
| S-EPMC9114281 | biostudies-literature