Impact of progressive resistance training on CT quantified muscle and adipose tissue compartments in pancreatic cancer patients.

ABSTRACT:

Objectives

Loss of body weight is often seen in pancreatic cancer and also predicts poor prognosis. Thus, maintaining muscle mass is an essential treatment goal. The primary aim was to investigate whether progressive resistance training impacts muscle and adipose tissue compartments. Furthermore, the effect of body composition on overall survival (OS) was investigated.

Methods

In the randomized SUPPORT-study, 65 patients were assigned to 6-month resistance training (2x/week) or a usual care control group. As secondary endpoint, muscle strength of the upper and lower extremities was assessed before and after the intervention period. Routine CT scans were assessed on lumbar L3/4 level for quantification of total-fat-area, visceral-fat-area, subcutaneous-fat-area, intramuscular

SUBMITTER: Wochner R 

PROVIDER: S-EPMC7703876 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature