Ontology highlight
ABSTRACT:
SUBMITTER: Abedin S
PROVIDER: S-EPMC7705269 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Journal of experimental pharmacology 20201126
Acute GVHD (aGVHD) is a significant complication after allogeneic hematopoietic cell transplantation (HCT), occurring in up to 70% of HCT recipients. Steroid-refractory aGVHD represents a subset of patients failing initial therapy and is particularly morbid, with only 30% of patients surviving long term. Better therapies are urgently required for these patients. Here, we discuss recent advancements in the management of SR-aGVHD. We review the currently available therapies for SR-aGVHD including ...[more]