Dataset Information

Simultaneous Measurement of Objective and Subjective Accommodation in Response to Step Stimulation.

ABSTRACT: Purpose:This study aimed to evaluate differences in objective and subjective accommodation dynamically and simultaneously. Methods:Thirty-four pre-presbyopic healthy volunteers (mean age ± SD, 41.0 ± 3.2 years) participated in this study. Initially, the reaction time for detecting a change in the target was measured at near. Dynamic accommodation was then monocularly recorded using an open-view Shack-Hartmann aberrometer and compared with the amplitude and velocity of subjective accommodation. Results:The objective amplitude of accommodation (0.97 ± 0.32 diopter [D]) was significantly greater than the subjective amplitude of accommodation (0.62 ± 0.43 D; P < 0.001). The accommodative velocity was significantly faster for the "before the accommodation" response time (0.47 ± 0.38 D/s) than the "after the accommodation" response time (0.21 ± 0.22 D/s; P = 0.007). Conclusions:The human eye under the monocular condition quickly adjusts to the focal plane to clearly archive the nearby object, and the focal plane thereafter is slowly and accurately adjusted to the visual target after visual recognition.

SUBMITTER: Hirota M

PROVIDER: S-EPMC7705395 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Simultaneous Measurement of Objective and Subjective Accommodation in Response to Step Stimulation.

Hirota Masakazu M Morimoto Takeshi T Miyoshi Tomomitsu T Fujikado Takashi T

Investigative ophthalmology & visual science 20201101 13

<h4>Purpose</h4>This study aimed to evaluate differences in objective and subjective accommodation dynamically and simultaneously.<h4>Methods</h4>Thirty-four pre-presbyopic healthy volunteers (mean age ± SD, 41.0 ± 3.2 years) participated in this study. Initially, the reaction time for detecting a change in the target was measured at near. Dynamic accommodation was then monocularly recorded using an open-view Shack-Hartmann aberrometer and compared with the amplitude and velocity of subjective a ...[more]

PMID: 33252633

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Project description:ImportanceTo date, no randomized clinical trial on the comparison between simultaneous and sequential bilateral cochlear implants (BiCIs) has been performed.ObjectiveTo investigate the hearing capabilities and the self-reported benefits of simultaneous BiCIs compared with those of sequential BiCIs.Design, setting, and participantsA multicenter randomized clinical trial was conducted between January 12, 2010, and September 2, 2012, at 5 tertiary referral centers among 40 participants eligible for BiCIs. Main inclusion criteria were postlingual severe to profound hearing loss, age 18 to 70 years, and a maximum duration of 10 years without hearing aid use in both ears. Data analysis was conducted from May 24 to June 12, 2016.InterventionsThe simultaneous BiCI group received 2 cochlear implants during 1 surgical procedure. The sequential BiCI group received 2 cochlear implants with an interval of 2 years between implants.Main outcomes and measuresFirst, the results 1 year after receiving simultaneous BiCIs were compared with the results 1 year after receiving sequential BiCIs. Second, the results of 3 years of follow-up for both groups were compared separately. The primary outcome measure was speech intelligibility in noise from straight ahead. Secondary outcome measures were speech intelligibility in noise from spatially separated sources, speech intelligibility in silence, localization capabilities, and self-reported benefits assessed with various hearing and quality of life questionnaires.ResultsNineteen participants were randomized to receive simultaneous BiCIs (11 women and 8 men; median age, 52 years [interquartile range, 36-63 years]), and another 19 participants were randomized to undergo sequential BiCIs (8 women and 11 men; median age, 54 years [interquartile range, 43-64 years]). Three patients did not receive a second cochlear implant and were unavailable for follow-up. Comparable results were found 1 year after simultaneous or sequential BiCIs for speech intelligibility in noise from straight ahead (difference, 0.9 dB [95% CI, -3.1 to 4.4 dB]) and all secondary outcome measures except for localization with a 30° angle between loudspeakers (difference, -10% [95% CI, -20.1% to 0.0%]). In the sequential BiCI group, all participants performed significantly better after the BiCIs on speech intelligibility in noise from spatially separated sources and on all localization tests, which was consistent with most of the participants' self-reported hearing capabilities. Speech intelligibility-in-noise results improved in the simultaneous BiCI group up to 3 years following the BiCIs.Conclusions and relevanceThis study shows comparable objective and subjective hearing results 1 year after receiving simultaneous BiCIs and sequential BiCIs with an interval of 2 years between implants. It also shows a significant benefit of sequential BiCIs over a unilateral cochlear implant. Until 3 years after receiving simultaneous BiCIs, speech intelligibility in noise significantly improved compared with previous years.Trial registrationtrialregister.nl Identifier: NTR1722.

Dataset Information

Simultaneous Measurement of Objective and Subjective Accommodation in Response to Step Stimulation.

Publications

Simultaneous Measurement of Objective and Subjective Accommodation in Response to Step Stimulation.

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