Ontology highlight
ABSTRACT:
SUBMITTER: Bosica G
PROVIDER: S-EPMC7705860 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20201124
A rapid route for obtaining unsymmetrical 1,2-dihydropyridines (1,2-DHPs) as opposed to 1,4-dihydropyridines (1,4-DHPs) has been achieved via a one-pot multicomponent Hantzsch reaction. A benign protocol has been developed for the preparation of various 1,2-dihydropyridine derivatives using heterogenized phosphotungstic acid on alumina support (40 wt %). High yields of over 75% have been accomplished in just 2-3.5 h after screening several heterogeneous catalysts and investigating the optimal re ...[more]