An evaluation of solid versus liquid transport media for high-risk HPV detection and cervical cancer screening on self-collected specimens.

ABSTRACT:

Background

The solid transport media is a small size card that allows fast, easy DNA extraction from a variety of biological samples. In 2016 we developed a solid media transport card; for that pilot study to control the self-collection we used a pseudo-self-collection technique. The current study expands this prior work using true self-collections and only the POI card, and aims to evaluate the solid media transport card to detect HR-HPV in self-samples compared to liquid transport media.

Methods

Ten thousand eight hundred eighty-five women between the ages of 30-59 with no screening for 3 years were enrolled. The self-collected sample was first applied to a new solid media transport card (Labeled as SC) then the brush placed in 6 ml ThinPrep liquid (Labeled as SL). Then a

SUBMITTER: Du H 

PROVIDER: S-EPMC7706049 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature