Ontology highlight
ABSTRACT:
SUBMITTER: Malagon M
PROVIDER: S-EPMC7707514 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Malagón Marta M Ramió-Pujol Sara S Serrano Marta M Amoedo Joan J Oliver Lia L Bahí Anna A Miquel-Cusachs Josep Oriol JO Ramirez Manel M Queralt-Moles Xavier X Gilabert Pau P Saló Joan J Guardiola Jordi J Piñol Virginia V Serra-Pagès Mariona M Castells Antoni A Aldeguer Xavier X Garcia-Gil L Jesús LJ
PloS one 20201201 12
Guidelines recommend routine screening for colorectal cancer (CRC) in asymptomatic adults starting at age 50. The most extensively used noninvasive test for CRC screening is the fecal immunochemical test (FIT), which has an overall sensitivity for CRC of approximately 61.0%-91.0%, which drops to 27.0%-67.0% for advanced adenomas. These figures contain a high false-positive rate and a low positive predictive value. This work aimed to develop a new, noninvasive CRC screening tool based on fecal ba ...[more]