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Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution.


ABSTRACT: OBJECTIVE:Our study planned to investigate the current positivity rate and distribution of the serologic markers of TTIs among male blood donors of the White Nile state, Sudan. RESULTS:The overall reported seropositive cases of TTIs was 15.91%, and percentages of anti-Human immunodeficiency virus 1/2 (anti-HIV1/2), Hepatitis B virus surface antigen (HBVsAg), anti-Hepatitis C virus (anti-HCV), and anti-Treponema palladium (anti-T. palladium) were 2.61%, 5.57%, 1.40%, and 5.72%, respectively. Out of 10897 donors examined, 0.59% had a serological sign of multiple infections. Furthermore, the odds of testing positive for TTIs were higher in the 28-37 age group (OR: 2.620, 95% CI: 2.324-2.955) and lower in the 38-47 age group (OR: 0.671, 95% CI: 0.567-0.794) compared to individuals of 18-27 years old. Likewise, it is more in individuals of Kosti (OR: 1.122, 95% CI: 0.987-1.277) and Rabak (OR: 1.354, 95% CI: 1.188-1.543) localities compared to Al Douiem locality. Anti-HIV/anti-T. palladium (27.70%) and anti-HIV/HBVsAg (23.07%) were the most frequently detected serologic markers of co-infections, P?=?0.002.

SUBMITTER: Ahmed EB 

PROVIDER: S-EPMC7708122 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution.

Ahmed Elnaim Bushra EB   Essa Areej Ahmed AA   Almugadam Babiker Saad BS   Ahmed Qawaeid Mohamed QM   Hussein Mofeeda Mohammed MM  

BMC research notes 20201130 1


<h4>Objective</h4>Our study planned to investigate the current positivity rate and distribution of the serologic markers of TTIs among male blood donors of the White Nile state, Sudan.<h4>Results</h4>The overall reported seropositive cases of TTIs was 15.91%, and percentages of anti-Human immunodeficiency virus 1/2 (anti-HIV1/2), Hepatitis B virus surface antigen (HBVsAg), anti-Hepatitis C virus (anti-HCV), and anti-Treponema palladium (anti-T. palladium) were 2.61%, 5.57%, 1.40%, and 5.72%, res  ...[more]

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