Exposure to acute normobaric hypoxia results in adaptions of both the macro- and microcirculatory system.
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ABSTRACT:
SUBMITTER: Mirna M
PROVIDER: S-EPMC7708486 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
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Exposure to acute normobaric hypoxia results in adaptions of both the macro- and microcirculatory system.
Mirna Moritz M Bimpong-Buta Nana-Yaw NY Hoffmann Fabian F Abusamrah Thaer T Knost Thorben T Sander Oliver O Hew Yayu Monica YM Lichtenauer Michael M Muessig Johanna M JM Bruno Raphael Romano RR Kelm Malte M Zange Jochen J Wilhelm Jilada J Limper Ulrich U Jordan Jens J Tank Jens J Jung Christian C
Scientific reports 20201201 1
Although acute hypoxia is of utmost pathophysiologic relevance in health and disease, studies on its effects on both the macro- and microcirculation are scarce. Herein, we provide a comprehensive analysis of the effects of acute normobaric hypoxia on human macro- and microcirculation. 20 healthy participants were enrolled in this study. Hypoxia was induced in a normobaric hypoxia chamber by decreasing the partial pressure of oxygen in inhaled air stepwisely (pO<sub>2</sub>; 21.25 kPa (0 k), 16.4 ...[more]
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