Fine particulate matter exposure during childhood relates to hemispheric-specific differences in brain structure.

ABSTRACT:

Background

Emerging findings have increased concern that exposure to fine particulate matter air pollution (aerodynamic diameter ≤ 2.5 μm; PM_2.5) may be neurotoxic, even at lower levels of exposure. Yet, additional studies are needed to determine if exposure to current PM_2.5 levels may be linked to hemispheric and regional patterns of brain development in children across the United States.

Objectives

We examined the cross-sectional associations between geocoded measures of concurrent annual average outdoor PM_2.5 exposure, regional- and hemisphere-specific differences in brain morphometry and cognition in 10,343 9- and 10- year-old children.

Methods

High-resolution structural T1-weighted brain magnetic resonance imaging (MRI) and NIH To

SUBMITTER: Cserbik D 

PROVIDER: S-EPMC7708513 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature