Ontology highlight
ABSTRACT:
SUBMITTER: Rivas Serna IM
PROVIDER: S-EPMC7709039 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Rivas Serna Irma Magaly IM Romito Ilaria I Maugeri Andrea A Lo Re Oriana O Giallongo Sebastiano S Mazzoccoli Gianluigi G Oben Jude A JA Li Volti Giovanni G Mazza Tommaso T Alisi Anna A Vinciguerra Manlio M
International journal of molecular sciences 20201110 22
Lipid catabolism and anabolism changes play a role in stemness acquisition by cancer cells, and cancer stem cells (CSCs) are particularly dependent on the activity of the enzymes involved in these processes. Lipidomic changes could play a role in CSCs' ability to cause disease relapse and chemoresistance. The exploration of lipid composition and metabolism changes in CSCs in the context of hepatocellular cancer (HCC) is still incomplete and their lipidomic scenario continues to be elusive. We ai ...[more]