Label-Free Near-Infrared Plasmonic Sensing Technique for DNA Detection at Ultralow Concentrations.

ABSTRACT: Biomolecular detection at a low concentration is usually the most important criterion for biological measurement and early stage disease diagnosis. In this paper, a highly sensitive nanoplasmonic biosensing approach is demonstrated by achieving near-infrared plasmonic excitation on a continuous gold-coated nanotriangular array. Near-infrared incident light at a small incident angle excites surface plasmon resonance with much higher spectral sensitivity compared with traditional configuration, due to its greater interactive volume and the stronger electric field intensity. By introducing sharp nanotriangular metallic tips, intense localization of plasmonic near-fields is realized to enhance the molecular perception ability on sensing surface. This approach with an enhanced sensitivity (4210

SUBMITTER: Chen S 

PROVIDER: S-EPMC7709993 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature