Roles of MicroRNAs in Bone Destruction of Rheumatoid Arthritis.
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ABSTRACT:
SUBMITTER: Zhao H
PROVIDER: S-EPMC7710907 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Roles of MicroRNAs in Bone Destruction of Rheumatoid Arthritis.
Zhao Hanxiao H Lu Aiping A He Xiaojuan X
Frontiers in cell and developmental biology 20201119
As an important pathological result of rheumatoid arthritis (RA), bone destruction will lead to joint injury and dysfunction. The imbalance of bone metabolism caused by increased osteoclast activities and decreased osteoblast activities is the main cause of bone destruction in RA. MicroRNAs (MiRNAs) play an important role in regulating bone metabolic network. Recent studies have shown that miRNAs play indispensable roles in the occurrence and development of bone-related diseases including RA. In ...[more]
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