Establishment of a Molecular Tumor Board (MTB) and Uptake of Recommendations in a Community Setting.

ABSTRACT: In the precision medicine era, molecular testing in advanced cancer is foundational to patient management. Molecular tumor boards (MTBs) can be effective in processing comprehensive genomic profiling (CGP) results and providing expert recommendations. We assessed an MTB and its role in a community setting. This retrospective analysis included patients with MTB recommendations at a community-based oncology practice January 2015 to December 2018; exclusions were death within 60 days of the MTB and/or no metastatic disease. Potentially actionable genomic alterations from CGP (immunohistochemistry, in-situ hybridization, next-generation sequencing) were reviewed bi-weekly by MTB practice experts, pathologists, genetic counselors, and other support staff, and clinical care recommendations were

SUBMITTER: VanderWalde A 

PROVIDER: S-EPMC7711773 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature