Ontology highlight
ABSTRACT:
SUBMITTER: Vimaleswaran KS
PROVIDER: S-EPMC7712587 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Journal of personalized medicine 20201025 4
The study by Jha et al. (2019) demonstrated an association of the single nucleotide polymorphism (SNP) rs2274907 A>T with coronary artery disease (CAD) in 100 CAD patients and 100 matched healthy controls from a South Indian population. There are serious concerns with regard to the interpretations of the study findings. The genotypes of the SNP are not in Hardy-Weinberg equilibrium (HWE) in both cases (<i>p</i> < 0.0001) and controls (<i>p</i> = 0.006), which is indicative of a technical error d ...[more]