Dietary fruit and vegetable intake, gut microbiota, and type 2 diabetes: results from two large human cohort studies.

ABSTRACT:

Background

Little is known about the inter-relationship among fruit and vegetable intake, gut microbiota and metabolites, and type 2 diabetes (T2D) in human prospective cohort study. The aim of the present study was to investigate the prospective association of fruit and vegetable intake with human gut microbiota and to examine the relationship between fruit and vegetable-related gut microbiota and their related metabolites with type 2 diabetes (T2D) risk.

Methods

This study included 1879 middle-age elderly Chinese adults from Guangzhou Nutrition and Health Study (GNHS). Baseline dietary information was collected using a validated food frequency questionnaire (2008-2013). Fecal samples were collected at follow-up (2015-2019) and analyzed for 16S rRNA sequencing and targeted

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC7712977 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature