Ontology highlight
ABSTRACT:
SUBMITTER: Fridrich A
PROVIDER: S-EPMC7713132 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Fridrich Arie A Modepalli Vengamanaidu V Lewandowska Magda M Aharoni Reuven R Moran Yehu Y
Nature communications 20201203 1
MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target regulation is considered crucial for animal physiology and development. However, this notion is based exclusively on studies in bilaterians, which comprise almost all lab model animals. To fill this phylogenetic gap, we characterize the functions of two Argonaute paralogs in the sea anemone Nematostella vectensis of the phylum Cnidaria, which is separated from bilaterians by ...[more]