How effective are the non-conventional ovarian stimulation protocols in ART? A systematic review and meta-analysis.

ABSTRACT:

Purpose

To compare the effectiveness of starting the ovarian stimulation on the early follicular phase ("Conventional") with the newer range of non-conventional approaches starting in the luteal phase ("Luteal"), random-start, and studies implementing them in DuoStim ("Conventional"+"Luteal").

Methods

Systematic review. We searched CENTRAL, PubMed, and Embase, on March 2020. We included randomized and non-randomized controlled trials that compared "Luteal," random-start ovarian stimulation or DuoStim with "Conventional"; we analyzed them by subgroups: oocyte freezing and patients undergoing ART treatments, both, in the general infertile population and among poor responders.

Results

The following results come from a sensitivity analysis that included only the low/moder

SUBMITTER: Glujovsky D 

PROVIDER: S-EPMC7714798 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature