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Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020.

ABSTRACT: We assessed the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Kawasaki disease (KD)-like multisystem inflammatory syndrome in a retrospective case-control study in France. RT-PCR and serological tests revealed SARS-CoV-2 infection in 17/23 cases vs 11/102 controls (matched odds ratio: 26.4; 95% confidence interval: 6.0-116.9), indicating strong association between SARS-CoV-2 infection and KD-like illness. Clinicians should keep a high level of suspicion for KD-like illness during the COVID-19 pandemic.

SUBMITTER: Toubiana J 

PROVIDER: S-EPMC7716402 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020.

Toubiana Julie J   Levy Corinne C   Allali Slimane S   Jung Camille C   Leruez-Ville Marianne M   Varon Emmanuelle E   Bajolle Fanny F   Ouldali Naim N   Chareyre Judith J   Béchet Stephane S   Elbez Annie A   Casanova Jean-Laurent JL   Chalumeau Martin M   Cohen Robert R   Cohen Jérémie F JF  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20201201 48

We assessed the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Kawasaki disease (KD)-like multisystem inflammatory syndrome in a retrospective case-control study in France. RT-PCR and serological tests revealed SARS-CoV-2 infection in 17/23 cases vs 11/102 controls (matched odds ratio: 26.4; 95% confidence interval: 6.0-116.9), indicating strong association between SARS-CoV-2 infection and KD-like illness. Clinicians should keep a high level of sus  ...[more]

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