Cerebrospinal fluid glutamate changes in functional movement disorders.
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ABSTRACT:
SUBMITTER: Demartini B
PROVIDER: S-EPMC7718900 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Cerebrospinal fluid glutamate changes in functional movement disorders.
Demartini Benedetta B Invernizzi Roberto William RW Campiglio Laura L Bocci Tommaso T D'Arrigo Andrea A Arighi Andrea A Sciacca Francesca F Galimberti Daniela D Scarpini Elio E Gambini Orsola O Priori Alberto A
NPJ Parkinson's disease 20201204 1
The aim of this study was to assess cerebrospinal fluid (CSF) concentrations of specific amino acids using a high-performance liquid chromatography system in a sample of patients with functional movement disorders (FMDs) and in a sample of controls. CSF levels of glutamate were significantly lower in patients with FMD than in controls. This finding argues in favor of glutamatergic dysfunction in the pathophysiology of FMD. ...[more]
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