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Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital.


ABSTRACT: Pirfenidone is an antifibrotic agent that has been proven to slow down the progression of idiopathic pulmonary fibrosis (IPF). The aim of this study was to evaluate the efficacy of low-dose pirfenidone (that is, less than 1200 mg/day). We retrospectively reviewed the medical records of patients with IPF. The patients were divided into the following three groups, those who were not treated with pirfenidone (control) and those who were treated with pirfenidone at doses

SUBMITTER: Song MJ 

PROVIDER: S-EPMC7719184 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital.

Song Myung Jin MJ   Moon Sung Woo SW   Choi Ji Soo JS   Choi Ji Soo JS   Lee Sang Hoon SH   Lee Su Hwan SH   Chung Kyung Soo KS   Jung Ji Ye JY   Kang Young Ae YA   Park Moo Suk MS   Kim Young Sam YS   Chang Joon J   Kim Song Yee SY  

Scientific reports 20201204 1


Pirfenidone is an antifibrotic agent that has been proven to slow down the progression of idiopathic pulmonary fibrosis (IPF). The aim of this study was to evaluate the efficacy of low-dose pirfenidone (that is, less than 1200 mg/day). We retrospectively reviewed the medical records of patients with IPF. The patients were divided into the following three groups, those who were not treated with pirfenidone (control) and those who were treated with pirfenidone at doses < 1200 mg/day (low-dose grou  ...[more]

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