Ontology highlight
ABSTRACT:
SUBMITTER: Mattsson-Carlgren N
PROVIDER: S-EPMC7721731 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mattsson-Carlgren Niklas N Palmqvist Sebastian S Blennow Kaj K Hansson Oskar O
Nature communications 20201207 1
Biomarkers have revolutionized scientific research on neurodegenerative diseases, in particular Alzheimer's disease, transformed drug trial design, and are also increasingly improving patient management in clinical practice. A few key cerebrospinal fluid biomarkers have been robustly associated with neurodegenerative diseases. Several novel biomarkers are very promising, especially blood-based markers. However, many biomarker findings have had low reproducibility despite initial promising result ...[more]