Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men.

ABSTRACT: Background: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied.

Objective: To describe patient-reported outcome and the association with bone integrity, fracture severity and future fracture risk among young and older men with distal radius fracture.

Methods: This prospective study includes 133 men with acute distal radius fracture, mean age 54 (range 21-88), who were followed for 12?months. They were categorized as younger (?15 was defined as poor outcome. Fractures were classified and radiographic displacement identified at initial presentation and follow-up. BMD was measured and FRAX 10-year probability of fracture calculated.

Results: Disability was higher in older men (DASH_median 10 vs 2; p?=?0.002); a clinically meaningful difference (?DASH?=?10, p?=?0.017) remained after adjustment for displacement, fracture classification and treatment method. Almost 50% of older men vs 14% in younger had poor outcome, p?median, IQR 45, 14;73) and risk of fracture (FRAX_{major osteoporotic} 14, 8;21).

Conclusion: Men over the age of 65 with a distal radius fracture are more likely to have post-fracture disability regardless of radiographic appearance. Fracture displacement, indicating impaired bone strength, is also more common and associated with an increased risk of fracture within 10-years. Secondary fracture prevention should therefore be considered in men presenting with distal radius fracture.

SUBMITTER: Egund L 

PROVIDER: S-EPMC7722451 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature