Dataset Information
The relationship between baseline diastolic dysfunction and postimplantation invasive hemodynamics with transcatheter aortic valve replacement.
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ABSTRACT:
Hypothesis: Diastolic dysfunction will modify the association between invasive hemodynamics postTAVR and mortality.
Methods: Patients with echocardiographic assessment of diastolic function and postTAVR invasive hemodynamic assessment were eligible for the present analysis. Diastology was classified as normal or abnormal (Stages 1 to 3). The aorto-ventricular index (AVi) was calculated as the difference between the aortic diastolic and the left ventricular end-diastolic pressure divided by the heart rate. AVi was categorized as abnormal (AVi?
Results: From 1339 TAVR patients, 390 were included in the final analysis. The mean follow-up was 3.3?±?1.7?years. Diastolic dysfunction was present in 70.9% of the abnormal vs 55.1% of the normal AVi group (P?
Conclusion: Diastolic dysfunction is prevalent among TAVR patients. Low AVi is an independent predictor for poor intermediate-term survival, irrespective of co-morbid diastolic dysfunction.
SUBMITTER: Bavry AA
PROVIDER: S-EPMC7724241 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
The relationship between baseline diastolic dysfunction and postimplantation invasive hemodynamics with transcatheter aortic valve replacement.
Clinical cardiology 20200922 12
<h4>Background</h4>Abnormal invasive hemodynamics after transcatheter aortic valve replacement (TAVR) is associated with poor survival; however, the mechanism is unknown.<h4>Hypothesis</h4>Diastolic dysfunction will modify the association between invasive hemodynamics postTAVR and mortality.<h4>Methods</h4>Patients with echocardiographic assessment of diastolic function and postTAVR invasive hemodynamic assessment were eligible for the present analysis. Diastology was classified as normal or abn ...[more]