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On-Demand Radial Electrodeposition of Alginate Tubular Structures.

ABSTRACT: We present an electrodeposition technique for fabricating tubular alginate structures. In this technique, two electrodes (anode and cathode) are suspended in a solution of alginate and insoluble calcium carbonate particles, and the application of an electrical potential produces a localized pH change at the anode surface causing suspended divalent cations to become soluble and cross-link the alginate. We robustly characterize how the fabrication parameters influence the rate of radial deposition on the anode, including deposition time, applied voltage, alginate concentration, type of divalent cation and concentration, and anode diameter. Furthermore, we produce gels with a range of tailorable features, including mechanical properties, dimensions (thick-ness and lumen size), customizable tubular geometries, and radial compositional heterogeneity.

SUBMITTER: Kingsley DM

PROVIDER: S-EPMC7725235 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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On-Demand Radial Electrodeposition of Alginate Tubular Structures.

Kingsley David M DM Capuano Jared A JA Corr David T DT

ACS biomaterials science & engineering 20190612 7

We present an electrodeposition technique for fabricating tubular alginate structures. In this technique, two electrodes (anode and cathode) are suspended in a solution of alginate and insoluble calcium carbonate particles, and the application of an electrical potential produces a localized pH change at the anode surface causing suspended divalent cations to become soluble and cross-link the alginate. We robustly characterize how the fabrication parameters influence the rate of radial deposition ...[more]

PMID: 33304999

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