Cytogenomic Abnormalities in 19 Cases of Salivary Gland Tumors of Parotid Gland Origin.
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ABSTRACT:
SUBMITTER: Zerjav M
PROVIDER: S-EPMC7725583 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Cytogenomic Abnormalities in 19 Cases of Salivary Gland Tumors of Parotid Gland Origin.
Zerjav Marie M DiAdamo Autumn A Grommisch Brittany B Katherine Amato A Chai Hongyan H Peng Gang G Li Peining P
Case reports in genetics 20201202
Salivary gland tumors (SGTs) of parotid origin are a group of diverse neoplasms which are difficult to classify due to their rarity and similar morphologic patterns. Chromosome analysis can detect clonal abnormalities, and array comparative genomic hybridization (aCGH) analysis can define copy number alterations (CNAs) from tumor specimens. Of the 19 cases of various types of SGTs submitted for cytogenomic analyses, an abnormal clone was detected in nine cases (47%), and CNAs were detected in 14 ...[more]
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