Ontology highlight
ABSTRACT:
SUBMITTER: Rajan PK
PROVIDER: S-EPMC7727670 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Rajan Pradeep Kumar PK Udoh Utibe-Abasi UA Sanabria Juan D JD Banerjee Moumita M Smith Gary G Schade Mathew Steven MS Sanabria Jacqueline J Sodhi Komal K Pierre Sandrine S Xie Zijian Z Shapiro Joseph I JI Sanabria Juan J
International journal of molecular sciences 20201124 23
Epigenetics, an inheritable phenomenon, which influences the expression of gene without altering the DNA sequence, offers a new perspective on the pathogenesis of hepatocellular carcinoma (HCC). Nonalcoholic steatohepatitis (NASH) is projected to account for a significant share of HCC incidence due to the growing prevalence of various metabolic disorders. One of the major molecular mechanisms involved in epigenetic regulation, post-translational histone modification seems to coordinate various a ...[more]