Ontology highlight
ABSTRACT:
SUBMITTER: Yuan J
PROVIDER: S-EPMC7728369 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Yuan Jiahui J Zhang Gongye G Li Xiaomei X Ma Qiujuan Q Cheng Weipeng W Wang Weiwei W Zhang Bing B Hu Tianhui T Song Gang G
International journal of molecular sciences 20201125 23
Ubiquitin-specific protease 39 (USP39), a member of the deubiquitinating enzyme family, has been reported to participate in cytokinesis and metastasis. Previous studies determined that USP39 functions as an oncogenic factor in various types of cancer. Here, we reported that USP39 is frequently overexpressed in human lung cancer tissues and non-small-cell lung cancer (NSCLC) cell lines. USP39 knockdown inhibited the proliferation and colony formation of A549 and HCC827 cells and decreased tumorig ...[more]