Unknown

Dataset Information

0

Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?


ABSTRACT: With the increase in use of cannabis and its shifting legal status in the United States, cannabis use has become an important research focus. While studies of other drug populations have shown marked increases in risky decision-making, the literature on cannabis users is not as clear. The current study examined the performance of 17 cannabis users and 14 non-users on the Balloon Analog Risk Task (BART) using behavioral, fMRI and effective connectivity methods. Significant attenuation was found in a functional pathway projecting from the dorsal anterior cingulate cortex (dACC) to the nucleus accumbens (NAc) in cannabis users compared to non-using controls as well as decreases in risk-taking behaviors. These findings suggest that cannabis users may process and evaluate risks and rewards differently than non-users.

SUBMITTER: Raymond DR 

PROVIDER: S-EPMC7728610 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

altmetric image

Publications

Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?

Raymond David R DR   Paneto Adrian A   Yoder Karmen K KK   O'Donnell Brian F BF   Brown Joshua W JW   Hetrick William P WP   Newman Sharlene D SD  

Frontiers in psychiatry 20201127


With the increase in use of cannabis and its shifting legal status in the United States, cannabis use has become an important research focus. While studies of other drug populations have shown marked increases in risky decision-making, the literature on cannabis users is not as clear. The current study examined the performance of 17 cannabis users and 14 non-users on the Balloon Analog Risk Task (BART) using behavioral, fMRI and effective connectivity methods. Significant attenuation was found i  ...[more]

Similar Datasets

| S-EPMC6895726 | biostudies-literature
| S-EPMC3786021 | biostudies-literature
| S-EPMC6867417 | biostudies-literature
| S-EPMC3307370 | biostudies-literature
| S-EPMC5548624 | biostudies-literature
| S-EPMC5879545 | biostudies-literature
| S-EPMC2799948 | biostudies-literature
| S-EPMC7229012 | biostudies-literature
| S-EPMC10073643 | biostudies-literature
| S-EPMC7294471 | biostudies-literature