Motor Point Stimulation in Spinal Paired Associative Stimulation can Facilitate Spinal Cord Excitability.

ABSTRACT: Paired associative stimulation at the spinal cord (spinal PAS) has been shown to increase muscle force and dexterity by strengthening the corticomuscular connection, through spike timing dependent plasticity. Typically, transcranial magnetic stimulation (TMS) and transcutaneous peripheral nerve electrical stimulation (PNS) are often used in spinal PAS. PNS targets superficial nerve branches, by which the number of applicable muscles is limited. Alternatively, a muscle can be activated by positioning the stimulation electrode on the "motor point" (MPS), which is the most sensitive location of a muscle to electrical stimulation. Although this can increase the number of applicable muscles for spinal PAS, nobody has tested whether MPS can be used for the spinal PAS to date. Here we investigate

SUBMITTER: Fok KL 

PROVIDER: S-EPMC7729006 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature