Ontology highlight
ABSTRACT:
SUBMITTER: Worner S
PROVIDER: S-EPMC7729625 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Wörner Samantha S Leier Julia J Michenfelder Nadine C NC Unterreiner Andreas-Neil AN Wagenknecht Hans-Achim HA
ChemistryOpen 20201211 12
To mimic the charge separation in functional proteins we studied flavin-modified peptides as models. They were synthesized as oligoprolines that typically form a polyproline type-II helix, because this secondary structure supports the electron transfer properties. We placed the flavin as photoexcitable chromophore and electron acceptor at the N-terminus. Tryptophans were placed as electron donors to direct the electron transfer over 0-3 intervening prolines. Spectroscopic studies revealed compet ...[more]