Ontology highlight
ABSTRACT:
SUBMITTER: Akahori Y
PROVIDER: S-EPMC7729873 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Akahori Yuichi Y Kato Hiroki H Fujita Takashi T Moriishi Kohji K Tanaka Yasuhito Y Watashi Koichi K Imamura Michio M Chayama Kazuaki K Wakita Takaji T Hijikata Makoto M
Scientific reports 20201210 1
Recent development of hepatitis B virus (HBV) culture systems has made it possible to analyze the almost all steps of the viral life cycle. However, the reproducibility of interaction between HBV and host cells seemed inaccurate in those systems because of utilization of cancer cell lines with a difference from hepatocytes in the majority of cases. In this study, in order to resolve this point, a novel HBV culture system using non-cancer-derived immortalized human hepatocytes derived cell lines, ...[more]