Ontology highlight
ABSTRACT:
SUBMITTER: Fedou C
PROVIDER: S-EPMC7729974 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Fédou Camille C Breuil Benjamin B Golovko Igor I Decramer Stéphane S Magalhães Pedro P Muller Françoise F Dreux Sophie S Zürbig Petra P Klein Julie J Schanstra Joost P JP Buffin-Meyer Bénédicte B
Scientific reports 20201210 1
Production of amniotic fluid (AF) is view as predominately driven by excretion of fetal urine (FU). However, the origin of AF peptides, often considered as potential biomarkers of developmental diseases, has never been investigated. Here, we evaluated the FU origin of AF peptides and if the AF peptide content can be used as a surrogate of FU. The abundance of endogenous peptides was analyzed by capillary electrophoresis coupled to mass spectrometry in 216 AF and 64 FU samples. A total of 2668 an ...[more]