Ontology highlight
ABSTRACT:
SUBMITTER: Ouni E
PROVIDER: S-EPMC7730167 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ouni Emna E Ruys Sebastien Pyr Dit SPD Dolmans Marie-Madeleine MM Herinckx Gaëtan G Vertommen Didier D Amorim Christiani A CA
International journal of molecular sciences 20201130 23
Currently, the extracellular matrix (ECM) is considered a pivotal complex meshwork of macromolecules playing a plethora of biomolecular functions in health and disease beyond its commonly known mechanical role. Only by unraveling its composition can we leverage related tissue engineering and pharmacological efforts. Nevertheless, its unbiased proteomic identification still encounters some limitations mainly due to partial ECM enrichment by precipitation, sequential fractionation using unfriendly ...[more]