Ontology highlight
ABSTRACT:
SUBMITTER: Said AI
PROVIDER: S-EPMC7730367 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20201201 23
The regioselective synthesis of <i>cis</i> and <i>trans</i> stereoisomers of variously functionalized octahydro[1,2,4]triazolo[4,3-<i>a</i>]quinazolin-5-ones was performed. The 2-thioxopyrimidin-4-ones used in the synthesis reacted with hydrazonoyl chlorides in a regioselective manner to produce the angular regioisomers [1,2,4]triazolo[4,3-<i>a</i>]quinazolin-5-ones rather than the linear isomers [1,2,4]triazolo[4,3-<i>a</i>]quinazolin-5-ones. The synthesis process took place with electronic con ...[more]