Ontology highlight
ABSTRACT:
SUBMITTER: Juric J
PROVIDER: S-EPMC7732334 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Jurić Julija J Kohrt Wendy M WM Kifer Domagoj D Gavin Kathleen M KM Pezer Marija M Nigrovic Peter A PA Lauc Gordan G
Aging 20201013 19
Glycan age is a recently developed biomarker based on glycans attached to immunoglobulin G (IgG). In large population cohorts, glycan age associates well with lifestyle and disease-risk biomarkers, while some studies suggested that glycan changes precede development of several age-associated diseases. In this study we evaluated effects of estrogen on the glycan age. Gonadal hormones were suppressed in 36 healthy young women by gonadotropin releasing hormone agonist therapy for 6 months. In 15 of ...[more]