Ontology highlight
ABSTRACT:
SUBMITTER: Hobbs CV
PROVIDER: S-EPMC7732413 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Hobbs Charlotte V CV Khaitan Alka A Kirmse Brian M BM Borkowsky William W
Frontiers in pediatrics 20201124
During the COVID-19 pandemic, children have had markedly different clinical presentations and outcomes compared to adults. In the acute phase of infection, younger children are relatively spared the severe consequences reported in adults. Yet, they are uniquely susceptible to the newly described Multisystem Inflammatory Syndrome in Children (MIS-C). This may result from the developmental "immunodeficiency" resulting from a Th2 polarization that starts <i>in utero</i> and is maintained for most o ...[more]