Ontology highlight
ABSTRACT:
SUBMITTER: Krieger MS
PROVIDER: S-EPMC7733879 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Krieger Madison S MS Moreau Joshua M JM Zhang Haiyu H Chien May M Zehnder James L JL Craig Morgan M
Patterns (New York, N.Y.) 20201106 9
A central challenge in medicine is translating from observational understanding to mechanistic understanding, where some observations are recognized as causes for the others. This can lead not only to new treatments and understanding, but also to recognition of novel phenotypes. Here, we apply a collection of mathematical techniques (<i>empirical dynamics</i>), which infer mechanistic networks in a model-free manner from longitudinal data, to hematopoiesis. Our study consists of three subjects w ...[more]