Dataset Information

Impact of COVID-19 on health-related quality of life in patients with cardiovascular disease: a multi-ethnic Asian study.

ABSTRACT:

Background

Little is known about the impact of the global coronavirus disease-2019 (COVID-19) pandemic on patients with cardiovascular disease (CVD), the biggest global killer and major risk factor for severe COVID-19 infections. We aim to explore the indirect consequences of COVID-19 on health-related quality of life (HRQoL) of patients with CVD.

Methods

Eighty-one adult outpatients with CVD were assessed using the EQ-5D, a generic health status instrument with five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), before and during the pandemic. Changes in the EQ-5D dimensional responses were compared categorically as well as using the dimension-specific sum-score (range 1-3, with a higher score indicating worse health). The responses and sum-score were compared using the exact test of symmetry and the paired t-test, respectively.

Results

These patients [mean age (SD) 59.8 (10.5); 92.6% males; 56% New York Heart Association (NYHA) functional class I] had coronary artery disease (69%), heart failure (28%), or arrhythmias (15%). None experienced change in NYHA class between assessments. About 30% and 38% of patients reported problems with at least one of the EQ-5D dimensions pre-pandemic and during the pandemic, respectively. The highest increase in health problems was reported for anxiety/depression (12.5% pre-pandemic vs 23.5% during pandemic; p?=?0.035) with mean domain-specific score from 1.12 (SD 0.33) to 1.25 (SD 0.46) (standardized effect size?=?0.373, p?=?0.012). There was no meaningful change in other dimensions as well as overall HRQoL.

Conclusion

The COVID-19 pandemic is associated with a significant worsening of the mental health of patients with CVD.

SUBMITTER: Lim SL

PROVIDER: S-EPMC7734458 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Publications

Impact of COVID-19 on health-related quality of life in patients with cardiovascular disease: a multi-ethnic Asian study.

Lim Shir Lynn SL Woo Kai Lee KL Lim Eleanor E Ng Faclin F Chan Mark Y MY Gandhi Mihir M

Health and quality of life outcomes 20201214 1

<h4>Background</h4>Little is known about the impact of the global coronavirus disease-2019 (COVID-19) pandemic on patients with cardiovascular disease (CVD), the biggest global killer and major risk factor for severe COVID-19 infections. We aim to explore the indirect consequences of COVID-19 on health-related quality of life (HRQoL) of patients with CVD.<h4>Methods</h4>Eighty-one adult outpatients with CVD were assessed using the EQ-5D, a generic health status instrument with five dimensions (m ...[more]

PMID: 33317547

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Project description:Background and objectiveTo date, the impact of the COVID-19 pandemic on life expectancy for the Asian American (AA) population has been reported in aggregate. This study provides estimates of life expectancy at birth before and during the pandemic, with a set of demographic, health, and socioeconomic risk factors for the four largest subgroups: Asian Indians, Chinese, Filipinos, and Vietnamese. These estimates are placed in context of the broader U.S. population.MethodsThis study uses age-specific all-cause mortality from CDC WONDER and population counts from the American Community Surveys. We apply methodologies to address variability in population sizes over time (smoothing) and data quality issues at older ages (Brass relational model life table system) to produce three sets of sex-specific life expectancy estimates by subgroup for 2019, 2020, and 2021.ResultsAlmost all estimates show that the four AA subgroups experienced greater losses between 2019 and 2020 than Whites. These losses ranged from 1.1 to 3.9 years, with the largest drops among Chinese women (2.0-2.4) and Filipino men (3.5-3.9). Under all scenarios, losses in life expectancy were considerably smaller in 2021 than in 2020 among the four subgroups - with several subgroups experiencing a modest rebound - but these improvements did not compensate for the large increases in death rates in 2020. Filipino men had the largest decline in life expectancy from 2019 to 2021 among the four subgroups (3.4-4.2 years), and Vietnamese men and women experienced large losses which continued into the second year of the pandemic.ConclusionsDespite high pre-pandemic life expectancies, AAs suffered a large, and rarely acknowledged, increase in mortality during the pandemic, with substantial heterogeneity across subgroups and between women and men. This variability is due in part to the pronounced differences in risk factors for infection and severity which have been documented within the AA population.

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Dataset Information

Impact of COVID-19 on health-related quality of life in patients with cardiovascular disease: a multi-ethnic Asian study.

Background

Methods

Results

Conclusion

Publications

Impact of COVID-19 on health-related quality of life in patients with cardiovascular disease: a multi-ethnic Asian study.

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