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Computational Analysis of the Hypothetical Protein P9303_05031 from Marine Cyanobacterium Prochlorococcus Marinus MIT 9303.


ABSTRACT: Prochlorococcus marinus MIT 9303 is a marine cyanobacterium found in sea waters. It was first isolated from a depth of 100 m in the Sargasso Sea in the year 1992. This cyanobacterium serves as a good model system for scientific research due to the presence of many desirable characteristics like smaller in size, ability to perform photosynthesis and the ease of culture maintenance. The genome of this cyanobacterium encodes for about 3022 proteins. Out of these 3022 proteins, few proteins were annotated as hypothetical proteins. We performed a computational study to characterize one of the hypothetical proteins "P9303_05031" to deduce its functional role in the cell using various bioinformatics techniques. After in-depth analysis, this hypothetical protein showed the conserved domain as of Hsp10 of molecular chaperonins of GroES. In this work, we have predicted the bidirectional best hits for the hypothetical protein P9303_05031 followed by the prediction of protein properties such as primary, secondary and tertiary structures. The existence of the Hsp10 domain indicates its role is essential for the folding of proteins during heat shock. This work represents the first structural and physicochemical study of the hypothetical protein P9303_05031 in Prochlorococcus marinus MIT 9303.

SUBMITTER: Sai Arun PP 

PROVIDER: S-EPMC7734504 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Computational Analysis of the Hypothetical Protein P9303_05031 from Marine Cyanobacterium Prochlorococcus Marinus MIT 9303.

Sai Arun Pv Parvati PP   Yarlagadda Vineetha V   Vijaya Laxmi Govindugari G   Salla Sumithra S  

Journal of integrative bioinformatics 20200330 1


Prochlorococcus marinus MIT 9303 is a marine cyanobacterium found in sea waters. It was first isolated from a depth of 100 m in the Sargasso Sea in the year 1992. This cyanobacterium serves as a good model system for scientific research due to the presence of many desirable characteristics like smaller in size, ability to perform photosynthesis and the ease of culture maintenance. The genome of this cyanobacterium encodes for about 3022 proteins. Out of these 3022 proteins, few proteins were ann  ...[more]

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