Ontology highlight
ABSTRACT:
SUBMITTER: Jia XH
PROVIDER: S-EPMC7734811 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Journal of experimental & clinical cancer research : CR 20201214 1
The enthusiasm for immune checkpoint inhibitors (ICIs), an efficient tumor treatment model different from traditional treatment, is based on their unprecedented antitumor effect, but the occurrence of immune-related adverse events (irAEs) is an obstacle to the prospect of ICI treatment. IrAEs are a discrete toxicity caused by the nonspecific activation of the immune system and can affect almost all tissues and organs. Currently, research on biomarkers mainly focuses on the gastrointestinal tract ...[more]