Dataset Information

Incidence and trend of preterm birth in China, 1990-2016: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To update the WHO estimate of preterm birth rate in China in 1990-2016 and to further explore variations by geographic regions and years of occurrence.

Design

Systematic review and meta-analysis.

Data sources

Pubmed, Embase, Cochrane Library and Sinomed databases were searched from 1990 to 2018.

Eligibility criteria

Studies were included if they provided preterm birth data with at least 500 total births. Reviews, case-control studies, intervention studies and studies with insufficient information or published before 1990 were excluded. We estimated pooled incidence of preterm birth by a random effects model, and preterm birth rate in different year, region and by livebirths or all births in subgroup analyses.

Results

Our search identified 3945 records. After the removal of duplicates and screening of titles and abstracts, we reviewed 254 studies in full text and excluded 182, leaving 72 new studies. They were combined with the 82 studies included in the WHO report (154 studies, 187 data sets in total for the meta-analysis), including 24?039?084 births from 1990 to 2016. The pooled incidence of preterm birth in China was 6.09% (95% CI 5.86% to 6.31%) but has been steadily increasing from 5.36% (95% CI 4.89% to 5.84%) in 1990-1994 to 7.04% (95% CI 6.09% to 7.99%) in 2015-2016. The annual rate of increase was about 1.05% (95% CI 0.85% to 1.21%). Northwest China appeared to have the highest preterm birth rate (7.3%, 95%?CI 4.92% to 9.68% from 1990 to 2016).

Conclusions

The incidence of preterm birth in China has been rising gradually in the past three decades. It was 7% in 2016. Preterm birth rate varied by region with the West having the highest occurrence.

SUBMITTER: Jing S

PROVIDER: S-EPMC7735132 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Incidence and trend of preterm birth in China, 1990-2016: a systematic review and meta-analysis.

Jing Shiwen S Chen Chang C Gan Yuexin Y Vogel Joshua J Zhang Jun J

BMJ open 20201212 12

<h4>Objectives</h4>To update the WHO estimate of preterm birth rate in China in 1990-2016 and to further explore variations by geographic regions and years of occurrence.<h4>Design</h4>Systematic review and meta-analysis.<h4>Data sources</h4>Pubmed, Embase, Cochrane Library and Sinomed databases were searched from 1990 to 2018.<h4>Eligibility criteria</h4>Studies were included if they provided preterm birth data with at least 500 total births. Reviews, case-control studies, intervention studies ...[more]

PMID: 33310797

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Project description:ImportancePreterm birth complications are the leading cause of death in children younger than 5 years worldwide. Despite advancing knowledge of risk factors and mechanisms related to preterm labor, the preterm birth rate has risen in most industrialized countries. Moreover, the burden of neonatal preterm birth remains unclear across the world.ObjectiveTo determine the trends in incidence and mortality of neonatal preterm birth at the global, regional, and national levels to quantify its burden from 1990 to 2019 using data from the 2019 Global Burden of Disease study.Design, setting, and participantsAnnual incident cases, deaths, age-standardized incidence rates (ASIRs), and age-standardized mortality rates (ASMRs) of neonatal preterm birth between 1990 and 2019 were collected from the 2019 Global Burden of Disease study. The percentage of relative changes in incident cases and deaths as well as the estimated annual percentage changes (EAPCs) of ASIRs and ASMRs were calculated to quantify their temporal trends. Correlations of EAPC of ASIRs and ASMRs with sociodemographic index (SDI) and universal health coverage index were evaluated by Pearson correlation analyses.ExposuresInfants born alive before 37 completed weeks of gestation between 1990 and 2019.Main outcomes and measuresIncident cases, deaths, ASIRs, and ASMRs of neonatal preterm birth.ResultsGlobally, the incident cases of neonatal preterm birth decreased by 5.26% from 16.06 million in 1990 to 15.22 million in 2019, and the deaths decreased by 47.71% from 1.27 million in 1990 to 0.66 million in 2019. The overall ASIR (EAPC = -0.19 [95% CI, -0.27 to -0.11]) and ASMR (EAPC = -2.09 [95% CI, -1.99 to -2.20]) decreased in this period. The ASIR of neonatal preterm birth increased by a mean of 0.25% (95% CI, 0.13%-0.38%) in high-SDI regions from 1990 to 2019. The ASMR of neonatal preterm birth increased by a mean of 2.09% (95% CI, 1.99%-2.20%) in Southern Sub-Saharan Africa in this period. A positive correlation was observed between EAPC of ASIR and SDI or universal health coverage index in 2019, while a negative correlation was observed between EAPC in ASMR and SDI or universal health coverage index in 2019 at national levels.Conclusions and relevancePreterm birth remains a crucial issue in children worldwide, with an increasing trend in ASIR in high-SDI regions and in ASMR in Southern Sub-Saharan Africa between 1990 to 2019. Efforts to reduce both the incidence and mortality of preterm births are essential.

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Dataset Information

Incidence and trend of preterm birth in China, 1990-2016: a systematic review and meta-analysis.

Objectives

Design

Data sources

Eligibility criteria

Results

Conclusions

Publications

Incidence and trend of preterm birth in China, 1990-2016: a systematic review and meta-analysis.

Similar Datasets

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