Effect of darifenacin on fecal incontinence in women with double incontinence.

ABSTRACT:

Introduction and hypothesis

To evaluate change in fecal incontinence symptom severity after 8 weeks of darifenacin therapy in patients with double incontinence-urgency urinary incontinence (UUI) and fecal incontinence. Important secondary outcomes included fecal incontinence symptom distress and impact on quality of life, fecal incontinence episodes, global impression of improvement and overactive bladder symptom distress and impact.

Methods

Prospective open-label cohort study of women presenting primarily with UUI, diagnosed with double incontinence and electing antimuscarinic therapy for UUI. Women ≥ 18 years with moderate or greater bothersome UUI and fecal incontinence of liquid/solid stool with St. Marks (Vaizey) score ≥ 12 were included. Subjects were treated with dari

SUBMITTER: Kissane LM 

PROVIDER: S-EPMC7736065 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature