Calibrated scintigraphic imaging procedures improve quantitative assessment of the cardiac sympathetic nerve activity.
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ABSTRACT:
SUBMITTER: Okuda K
PROVIDER: S-EPMC7736873 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
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Calibrated scintigraphic imaging procedures improve quantitative assessment of the cardiac sympathetic nerve activity.
Okuda Koichi K Nakajima Kenichi K Kitamura Chiemi C Kirihara Yumiko Y Hashimoto Mitsumasa M Kinuya Seigo S
Scientific reports 20201214 1
The <sup>123</sup>I-labeled meta-iodobenzylguanidine (MIBG) is an analogue of noradrenaline that can evaluate cardiac sympathetic activity in scintigraphy. Quantitative analysis of <sup>123</sup>I-MIBG images has been verified in patients with heart failure and neurodegenerative diseases. However, quantitative results differ due to variations in scintigraphic imaging procedures. Here, we created and assessed the clinical feasibility of a calibration method for <sup>123</sup>I-MIBG imaging. The c ...[more]
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