Ontology highlight
ABSTRACT:
SUBMITTER: Manjarin R
PROVIDER: S-EPMC7737964 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Manjarin Rodrigo R Maj Magdalena A MA La Frano Michael R MR Glanz Hunter H
PloS one 20201215 12
The generation of large metabolomic data sets has created a high demand for software that can fit statistical models to one-metabolite-at-a-time on hundreds of metabolites. We provide the %polynova_2way macro in SAS to identify metabolites differentially expressed in study designs with a two-way factorial treatment and hierarchical design structure. For each metabolite, the macro calculates the least squares means using a linear mixed model with fixed and random effects, runs a 2-way ANOVA, corr ...[more]