Ontology highlight
ABSTRACT:
SUBMITTER: Chen T
PROVIDER: S-EPMC7739004 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Chen Tonglei T Chen Zhenshi Z Lian Xiaoning X Wu Weidong W Chu Lei L Zhang Shaoru S Wang Lihui L
Journal of Cancer 20210101 2
<b>Objective:</b> To investigate the high expression of MUC15 in promoting proliferation, migration and invasion in osteosarcoma (OS) cell and its potential mechanism. <b>Methods:</b> The expressions of MUC15 in OS patients were analyzed from GEO Datasets, tumor cell lines and clinical samples. The roles of MUC15 in OS were explored by CCK-8, flow cytometry, transwell and western blot assay, respectively. <b>Results:</b> MUC15 was highly expressed in osteosarcoma, and there was a significant neg ...[more]