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Distinguishing Felsenstein Zone from Farris Zone Using Neural Networks.

ABSTRACT: Maximum likelihood and maximum parsimony are two key methods for phylogenetic tree reconstruction. Under certain conditions, each of these two methods can perform more or less efficiently, resulting in unresolved or disputed phylogenies. We show that a neural network can distinguish between four-taxon alignments that were evolved under conditions susceptible to either long-branch attraction or long-branch repulsion. When likelihood and parsimony methods are discordant, the neural network can provide insight as to which tree reconstruction method is best suited to the alignment. When applied to the contentious case of Strepsiptera evolution, our method shows robust support for the current scientific view, that is, it places Strepsiptera with beetles, distant from flies.

SUBMITTER: Leuchtenberger AF

PROVIDER: S-EPMC7743852 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Distinguishing Felsenstein Zone from Farris Zone Using Neural Networks.

Leuchtenberger Alina F AF Crotty Stephen M SM Drucks Tamara T Schmidt Heiko A HA Burgstaller-Muehlbacher Sebastian S von Haeseler Arndt A

Molecular biology and evolution 20201201 12

Maximum likelihood and maximum parsimony are two key methods for phylogenetic tree reconstruction. Under certain conditions, each of these two methods can perform more or less efficiently, resulting in unresolved or disputed phylogenies. We show that a neural network can distinguish between four-taxon alignments that were evolved under conditions susceptible to either long-branch attraction or long-branch repulsion. When likelihood and parsimony methods are discordant, the neural network can pro ...[more]

PMID: 32637998

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