Unknown

Dataset Information

0

FAN-C: a feature-rich framework for the analysis and visualisation of chromosome conformation capture data


ABSTRACT: Chromosome conformation capture data, particularly from high-throughput approaches such as Hi-C, are typically very complex to analyse. Existing analysis tools are often single-purpose, or limited in compatibility to a small number of data formats, frequently making Hi-C analyses tedious and time-consuming. Here, we present FAN-C, an easy-to-use command-line tool and powerful Python API with a broad feature set covering matrix generation, analysis, and visualisation for C-like data (https://github.com/vaquerizaslab/fanc). Due to its compatibility with the most prevalent Hi-C storage formats, FAN-C can be used in combination with a large number of existing analysis tools, thus greatly simplifying Hi-C matrix analysis.

Supplementary Information

The online version contains supplementary material available at 10.1186/s13059-020-02215-9.

SUBMITTER: Kruse K 

PROVIDER: S-EPMC7745377 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4324155 | biostudies-literature
| S-EPMC4696798 | biostudies-literature
| S-EPMC4831724 | biostudies-literature
| S-EPMC5800693 | biostudies-literature
| S-EPMC3797596 | biostudies-literature
| S-EPMC4639323 | biostudies-literature
| S-EPMC3874837 | biostudies-literature
| S-EPMC7140825 | biostudies-literature
| S-EPMC4818521 | biostudies-literature
| S-EPMC3899129 | biostudies-literature