Ontology highlight
ABSTRACT:
SUBMITTER: Arneson A
PROVIDER: S-EPMC7745770 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Arneson Adriana A Felsheim Brooke B Chien Jennifer J Ernst Jason J
NAR genomics and bioinformatics 20201217 4
ConsHMM is a method recently introduced to annotate genomes into conservation states, which are defined based on the combinatorial and spatial patterns of which species align to and match a reference genome in a multi-species DNA sequence alignment. Previously, ConsHMM was only applied to a single genome for one multi-species sequence alignment. Here, we apply ConsHMM to produce 22 additional genome annotations covering human and seven other organisms for a variety of multi-species alignments. A ...[more]