Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC7746340 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Zhang Junfeng J Sun Hui H Liu Songsong S Huang Wenjie W Gu Jianyou J Zhao Zhiping Z Qin Huan H Luo Liwen L Yang Jiali J Fang Yongfei Y Ge Jiayun J Ni Bing B Wang Huaizhi H
Aging 20201118 22
Pancreatic ductal adenocarcinoma (PDAC) is severely affecting the health and lives of patients. Clarifying the composition and regulatory factors of tumor immune microenvironment (TIME) is helpful for the treatment of PDAC. We analyzed the unique TIMEs and gene expression patterns between PDAC and adjacent normal tissue (ANT) using Gene Expression Omnibus (GEO) to find new immunotherapy targets. The Cancer Genome Atlas (TCGA) datasets were used to elucidate the possible mechanism of which tumor- ...[more]